In podcast #15, we’ll meet two researchers with very different approaches to tissue regeneration. We met both at the 2006 Regenerate World Congress in April.

First we’ll hear from Dr. Kevin Shakesheff  of the University of Nottingham. He is developing new scaffolds from a familiar material: polylactic acid, the same stuff that makes up absorbable sutures. Dr. Shakesheff imagines outfitting surgeons with a syringe full of polylactic acid that is enhanced with growth factors — or even the patient’s own cells — to inject into an area that needs help to heal.

Our second interviewee, Dr. Nicholas Rhodes of the University of Liverpool, would like to do away with scaffolds altogether. Rather than introduce bioengineered materials into patients, he’d rather persuade a patient’s cells to do their own bioengineering. Dr. Rhodes is prompting regeneration by harnessing and directing the body’s natural inflammatory response.

Hosts Leah Kauffman and John Murphy. Interview by Leah Kauffman.

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